male patient 50 ys old , presented clinically with generalized lymphadenopathy (cervical, axillary & inguinal) , excision biopsy from inguinal LN was done; microscopically there is partial effacement with montonous small lymphocytes , with irregular nuclei and pale cytoplasm  
My question: Is this a case of mantle cell lymphoma?  
Thanks

Mueller-Hermelink 2007-07-11 19:32	Please add the images of the l.n.
ehyjek 2007-07-13 04:45	Can you perform some immunostainings on this LN such as CD20, CD3, CD5 ,and BCL-1?
hurwitz 2007-07-14 22:11	High power images (6,7,8,9,10) allow the diagnosis of lymphoma, composed mainly of small lymphoid cells. On image 6 an area with large cells is seen.   Dr.Hyjek inquired already if you have any facilities for immunostains. Coud you please be so kind and let us know?
mona_rashed 2007-07-15 09:23	Thanks Dr. Nina , very soon I'll send the immunostain images
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