a young boy, 14 years old with lymphadenopathy and fever.  
biopsy (cerba) had shown a lymphoblastic lymphoma bcl2+, bcl6-, CD3-, CD5-, CD20-, and 80% of cells with Ki67.  
 
8 month later, we find 21% of blast in blood sample and 67.5% in bone marrow. These cells were MPO -  
Immunology of blood had shown : CD 34+, CD3-, CD19+,CD22-, CD79a-, HLA DR-,  
 
Then intracytoplasmic marking : cCD22- cCD3- cCD10- cIgM  
 
We just want to know what type of acute lymphoblastic leukemia do we have

awaoumar20000 2014-08-28 16:40	[new images sent by email]
SergeyN 2014-08-28 20:44	Looks like a typical B-precursor leukemia to me.     P.S. CD45/CD19 plot is very good for viewing B-lineage blasts
abohady 2014-09-02 19:47	Does CD19 is enough to define lineage as lymphoid?
abohady 2014-09-02 19:59	CD22,CD79a or CD10 one of them must be strong positive or two of them weak positive if CD19 weak positive,according WHO 2008.
abohady 2014-09-02 20:01	CD22,CD79a or CD10 one of them must be strong positive or two of them weak positive if CD19 weak positive,according WHO 2008 to define lineage as B-lymphoid.
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