CASE IS READY FOR REVIEW:  
 
77 yrs old male with small intestinal tumor resected due to intestinal perforation. No data about previous enteropathy or sprue.  
MACRO: 23 cm small intestinal fragment with 4x2 cm ulcer and perforation.  
 
HISTO: Vaguelly nodular small medium large cell infiltrate with epitheliothropism and perifocal granulomas and focal necroses.  
At periphery- blunting of villi with lymphothropism.  
 
IH: CD3/CD2/CD7+ > CD5+(weaker); PD1+; CD4/CD8+; CD56+(weak focal); TCR-BETA  
-/+(weak focal); CD30-/+(focal); CD103/GRANZYME B/TIA1(-); KI67 index up to 50%.  
 
PHHOTO: the last number means BLOCK number (3 blocks presented 1, 7, 8).  
NEW system of virtual slides applied (Leica): please refer, if not opening in separate browser frame.  
 
PROPOSAL: Aggressive T NHL (MEITL like), probably associated with enteropathy (?). Exulceration and perforation vs just T NHL NOS (intestinal).  
 
Thanx2021.

tzankov 2021-01-20 09:09	Nice case. The findings are consistent with MEITL. CD30 expression is rather typical.
ugnius 2021-01-20 09:15	Thanx and All the Best!