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NLP HL vs PTGC (1857) » CD3 nodule 1.jpg
Filename: CD3 nodule 1.jpg
[NLP HL vs PTGC]
16yrs old male presenting with inguinal lymphadenopathy for 2 years. Biopsy is performed. 2x is a my last choice to demonstrate the panoramic view:)  
HISTO: There are some large lymphoid nodules between normal follicles with popcorn and Hodgin like cells (some of it is crushed), clusters of histyocytes and residual GC cells.  
IH: The nodules with CD23+/CD21 network, with admixture CD20+ and CD3+ lympho's (in some- predominant CD20, in one (numbered 1)- CD3). There are activated CD30+/CD15- paracortical cells. EBC LMP1+ cells are absent. There are CD68+ macrophages in follicles and nodules. The single large cells CD30 (+). Some cells EMA (+) in nudules, but not atypical and large ones. Residual GC cells are CD10+ (single). Some sinus histyocytes S100+.  
 
PROPOSAL: Nodular Lympho Predominant Hodgkin's Lymphoma >>> PROGRESSIVE TRANSFORMATION OF GERMINAL CENTERS .  
Thank you for comments.
Sender: ugnius
2006-05-26 08:05
INCTR - EBMWG Hematopathology Online

Last modified: 2006-05-26 08:05:05