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A DD between florid PTGC and pediatric NMZL is not possible M /18yrs (22624) » 5.jpg
Filename: 5.jpg
[A DD between florid PTGC and pediatric NMZL is not possible M /18yrs]
18 yrs male. Lymph node biopsy (retroauricular) was done.  
HISTO: PTGC like picture with marginal zone expansion and irregular folliculothropism.  
MOLEC'S: IgH/IgK clone (PCR).  
IH: CD20+; CD43(-/+); IgM(-); IgD(-); Bcl2+; Ig lambda+ slightly > Ig kappa (no definite restriction); strange/aberant(?) Bcl6(+) ~70%; CD10(-); CyclinD1(-). Ki67 ~20%.  
 
PROPOSED DIAGNOSIS: Marginal zone lymphoma, pediatric type.  
 
Thankyoualot.  
 Sender: ugnius
 2010-07-13 07:55
INCTR - EBMWG Hematopathology Online

Last modified: 2010-07-13 07:55:14