32 yrs old male with disseminated lymhadenopathy and suspition of lymphoma. Lateral neck lymph node was taken.
HISTO: The pale nodules with histyocytic infiltrates, coalescent nodules of acellular necrosis, crescentic histiocytes MPO+/CD68+, predominating CD8+ cells around. Some T salt'n'pepper nodules and reactive follicles are present. BUT... Some nodules with HL like giant cells CD30+ CD15-. Some large perinecrotic cells CD15+ CD30-(maybe histiocytic? granuliocytic?). IH: Giant cells: CD30+ CD15- ALK1- EBVLMP1-; PALE AREAS (PRENECROTIC/HISTIOCYTIC): CD8 slightly >CD4 (mixture), CD68+/MPO+ histyocytes. PROPOSAL: Necrotic/Kikuchi lymphadenitis with HL like cells. Thank you for your attention.
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Last modified: 2007-07-04 09:39:38