27 yrs old male (consultation case: parafin blocks only) with anemia, leucocytosis, thrombocytopenia, BLASTS 16% (blood). Dry tap (BM aspirate).  
HISTO: on the slides. The lipocytes are absent. M/E ratio >10/1 (erythroid islands are not easy vissible at all). There are some central reactive lymphoid infiltrates.  
IH: pending. CD34+ neovascularity without excess of CD34+ stem cells.  
CD61+ small, medium and large mega's: hypo, hyper- lobated with emperipolesis with slight clustering. Fe deposits are absent.  
 
PROPOSAL: Chronic myeloproliferative disease, most probably CML with POSSIBLE population of the "blasts"???.  
PROPOSED DIAGNOSIS: ACUTE MYELOLEUKAEMIA. Immunophenotype: CD34-MPO+Bcl2+CD68/CD117-/+.