36 yrs old Lady with lateral neck lymph node biopsy (with intraoperative consult).
HISTO: A lot of clustered in nodules mononuclear giant cells with cHL IH: LCA(-)(?); OCT2/BOB1(-); CD20(-); CD30/CD15+. Background- slightly pleomorphic T cells with focal CD23 FDC nodular networks and HEV's. IH: fully retained T (CD3/CD2/CD/CD7+; CD10(-); Bcl6+ (focal). EBV LMP1/EBER(-).
STRANGE THINGS: Ki67 index much more distributed, than GIANT CELLS. Bcl2 signal FAINT and WEAK in T population. CYTOLOGICALLY T population abnormal and larger than usual. LCA doubtfull, CD3 golgi like (positive) in giant cells (?). "Nishing" in CD7 and CD3(?).