59 yrs old female with mediastinal open biopsy.  
HISTO: slightly nodular architecture with admixture of T and B cells and interstitial large lobated cells with retained (PM LBCL) B programme.  
IH: more close to PMLBCL: CD20/Pax5+ (strong); CD79a+; CD30+/- (faint); CD15(-); LCA+; EBV LMP1/EBER(-); CD23+; Bcl2/Bcl6+; CyclinD1(-); Mum1+; Oct2/BOB1+; EMA/CD10(-).  
CLONALITY (interesting): IGH clonal/oligoclonal (FR2); IGK polyclonal; TCRB polyclonal; TCRG clonal in polyclonal background.  
 
PROPOSAL: Grey zone lymphoma with PM LBCL (IH) and CHL (histo) features.  
 
Thank you for collaboration.