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Pediatric nasal teratoma with blastic proliferation (601052) » Blasts.jpg
Filename: Blasts.jpg
[Pediatric nasal teratoma with blastic proliferation]
9 days old baby (gender not specified) with resected nasopharyngeal tumor (inherited).  
MACRO: Polypoid epithelium covered white 1,9x1,4x0,9 cm fragment and 3 smaller brown tissue pieces.  
HISTO: Chondroid, glandular, epithelial and glial/ganglial structures with choroid plexus like elements (mature teratoma). Exulceration, covered by granulation tissue.  
In stroma, perivascular cuffs of atypical "blastoid" eosinophilic cells with eccentric nuclei, focal maturation and immunophenotype of myeloid line with some TdT+ Pax5+ B haematogone admixture. Any mega- or erythroid- elements present (no signs of bi or trilineage diff).  
 
PROPOSAL:  
Mature (nasopharyngeal) teratoma with myeloid blastic and smaller B lymphoblastic prolfieration (extramedulary haematopoiesis like?), probably benign.  
 
Thanxforalldone.
Sender: ugnius
2014-10-05 12:58
INCTR - EBMWG Hematopathology Online

Last modified: 2014-10-05 12:58:43