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CLL and malignant vascular tumor. Clusters of blasts TdT+,CD3+ of uncertain significance. (6553) » BONE sarcoma clefts 1.jpg
Filename: BONE sarcoma clefts 1.jpg
[CLL and malignant vascular tumor. Clusters of blasts TdT+,CD3+ of uncertain significance.]
Female, 60yrs.  
History: chronic lymphocytic leukemia from 2001 (only cytology, review impossible).  
Tumor of the femur nowadays, biopsy from femur.  
Micro: fascicles and whorls of spindle cells, abundant, sometimes pigmented cytoplasm, slight nuclear polymorphism, mitotic figures and clusters of small T lymphocytes, with scarce cytoplasm, irregular angulated nuclei.  
IH spindle cells: CyclinD1+ (nuclear), Ki67+ 20%, Bcl2+ (weak).  
PanCk/CD21/CD23/EMA/AsmAct/Des/S100/CD117/CD34/ER (-).  
IH lymphoid cells: CD3+, Tdt+, Cd5+, Ki67+ 80%, Cd1a+, CD20-, CD23-.  
 
Working diagnosis: dendritic cell sarcoma AND T lymphoblastic lymphoma.  
Thanking you in anticipation.
 Sender: ugnius
(case: mesrai1) 		2008-11-28 16:02
INCTR - EBMWG Hematopathology Online

Last modified: 2008-11-28 16:02:59