77 yrs old lady underwent inguinal lymphnodectomy due to "suppuration".  
Virtual slides: Apperio.  
Photo: from virtual slides.  
HE: Sinusoid, slightly nodular and difusse perinodal infiltrate of large- medium sized cells with oval vesiculated, "anaplastic" lobated and rarelly wrinckled nuclei and admixture of eosinophils and plasmacytes. Prominent central necrosis is present.  
IH: CD68+; S100+ ; CD4+; Bcl6+; CD1a+<5% (sic!);  
PanCK/EMA(-); CD20/CD79a/Pax5(-); Igkappa/lambda(-); CD3(-); HMB45/MelanA(-); CD21/CD23(-); Ki67(+/+++) 60%; CD30(-); TdT/CD34/CD117(-); CD15/MPO(-); Mum1(-);  
 
PARALEL SIMILAR PEDIATRIC CASE: https://www.ipath-network.com/ipath/object/view/1333  
 
PROPOSAL: Langerhans cell sarcoma in the lymph node with perinodal spread.  
Thank you for being 2gether.