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A DD between florid PTGC and pediatric NMZL is not possible M /18yrs (22624) » Bcl6 nodule 2.jpg

Filename: Bcl6 nodule 2.jpg
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A DD between florid PTGC and pediatric NMZL is not possible M /18yrs]

18 yrs male. Lymph node biopsy (retroauricular) was done.
HISTO: PTGC like picture with marginal zone expansion and irregular folliculothropism.
MOLEC'S: IgH/IgK clone (PCR).
IH: CD20+; CD43(-/+); IgM(-); IgD(-); Bcl2+; Ig lambda+ slightly > Ig kappa (no definite restriction); strange/aberant(?) Bcl6(+) ~70%; CD10(-); CyclinD1(-). Ki67 ~20%.

PROPOSED DIAGNOSIS: Marginal zone lymphoma, pediatric type.

Thankyoualot.

Sender: ugnius

2010-07-13 07:56
INCTR - EBMWG Hematopathology Online

original image: Bcl6 nodule 2.jpg (232.4 KB)

Last modified: 2010-07-13 07:56:19