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blastic plasmacytoid dendritic cell neoplasm M / 78 (22667) » HE 7.jpg
Filename: HE 7.jpg
[blastic plasmacytoid dendritic cell neoplasm M / 78]
78yrs old male with erythremia history in 1999 (no histo verified). Due to systemic lymphadenopathy the lymph node biopsy and skin biopsy from generalized papular eruption were taken.  
HISTO: NODE: The diffuse infiltration of medium sized cells with oval and irregular nuclei with focal "pale" zones. SKIN: Leukemoid perivascular periadnexal infiltrates (not included yet and not IH-typed).  
IH: LCA+; Bcl2+; CD4+ (low quality); CD43+; CD56+/-; CD7+; TdT(-/+); CD68(-); CD20/Pax5/CD3/CD2/CD5(-); MPO(-); CD117(-)(focal positivity in T cell enreached pale areas?).  
 
PROPOSED DIAGNOSIS: Plasmacytoid dendritic cell tumor in the lymph node and skin.  
The link: https://www.ipath-network.com/inctr/object/view/19542  
 
Thankyou.
Sender: ugnius
2010-07-13 08:45
INCTR - EBMWG Hematopathology Online

Last modified: 2010-07-13 08:45:29