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Dermatopathic lymphadenitis, rule out focal T-NHL (3546) » lymph nod, HE, x 10.jpg
Filename: lymph nod, HE, x 10.jpg
[Dermatopathic lymphadenitis, rule out focal T-NHL]
We present here a new case of enlarged right inguinal lymph node that was extirpated in a 47-year-old Bosnian male. He has been diagnozed with Mycosis fungoides seven years ago (patch phase).  
The yellowish, soft lymph node measured 3.5x1 cm.  
Microscopically, architecture of the lymph node was mainly preserved. In interfollicular areas, we noticed the presence of foamy cells filled with a dark pigment along with eosinophils and plasma cells.  
No signs of the spread of mycosis fungoides to the lymph node.  
Special staining: Fontana (positive).  
Immunohistochemistry: CD1a (positive), S100 (positive within the dendritic cells).  
Clinically, no signs of the spread of mycosis fungoides.  
Histopathological diagnosis: Langerhans hystiocytosis, reactive changes  
or other entity unrelated to the primary disease?
Sender: semir
2007-08-14 10:26
INCTR - EBMWG Hematopathology Online

Last modified: 2007-08-14 10:26:54