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reactive lymphadenopathy DD early Castleman (3654) » CD68.jpg
Filename: CD68.jpg
[reactive lymphadenopathy DD early Castleman]
We present a new case of the enlarge left supraclavicular lymph node in a 22-year-old Bosnian girl.  
Six months ago she also got the biopsy of the lymph node. The diagnosis was a reactive lymph node.  
Now, lymph node got a preserved architecture with both primary and secondary follicles and with proliferation and polarization of its marginal zone. Focally, reduction of germ centers is present. Interfollicular areas (red blood cells, eosinophils, erytroblasts, plasma cells) are increased along with proliferation of blood vessels.  
IHQ: CD20(+), CD45RA(+), CD5(+), Bcl-2 (+/-), Kappa(+), Lambda(+), IgM(+), IgD(+) and CD43 (stains T-lymphocytes).  
Question: Is this again only reactive lymph node or malignant alteration is going to occur?  
Thanks in advance for your opinion!
Sender: semir
2007-09-21 16:52
INCTR - EBMWG Hematopathology Online

Last modified: 2007-09-21 16:52:54