53 yrs old man underwent splenectomy due to hemoperitoneum and intraabdominal bleeding clinics.  
MACRO: Spleen 7,5x6x2,5cm with tears up to 3,5cm inthe capsule.  
HISTO: The infiltration of CD68+ histyoid cells with irregular deformed nuclei, eosinohilic PAS+ cytoplasm and immature CD34- MPO+ CD34- CD1a- S100- and mature myoeloid cell infiltration in the sinuses expanding the red pulp. There are some micoabscesses with eosinophils.  
FULL IH: Histyoid cells: CD68(+++) 100%, S100(++)20%, CD1a/MPO(-), CD4(+/++) 90%, Ig kappa/lambda (+/++)70%, Bcl2(-), Hb(+)40%.  
Immature myeloid population: MPO+ NASDE+CD34-CD117-. Ki67 in red pulp 30%. Follicles and sparse agregates: CD20+. Peritrabecular and interstitial lymphos: CD3+/Bcl2+. CD4/CD8 ~ 1/1. CD30+ single cells. Plasmacytes (partly- CD138+/Bcl2+) polytypic: Ig kappa/Ig lambda+. Single CD117+ mastocytes. Single CD61+ megakaryocytes. Sinusoids: CD8+.  
CLINICS: The patient underwent polytrauma and died son after laparotomy.  
 
PROPOSAL: Extramedulary hematopoesis due to myeloproliferative disease (CML? oth.?) with possible erythrophagocytosis? OTHER?  
 
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