STORY: 71 yrs old female with right sided lateral lymphadenopathy (4x6x7 cm confluent immobile nodes for 1 year). CRB elevated. Slight monocytosis is present.

CLIN DIAGNOSIS: "Lymphoma?".

HISTO: Confluent  hypercellular and pleomorphic"epithelioid" granulomas with acellular necrosis ("caseating") with TBC like appearance.

IH: A lot of Langerhans cells within granulomas: CD1a+; CD68+; S100+ with admixture of histiocytes, multinucleated cells...

PROPOSED DIAGNOSIS: TBC granulomatous lymphadenitis (enriched LC) vs Langerhans cell histiocytosis: "granulomatous, TBC like pattern".

PROBLEMATIC ASPECTS: 1. The absense of Eos? 2. The theorethical possibility of association with other LPL (not present there?)?

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