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CLL, lymphoplasmacytoid variant (3783) » NASDE 1.jpg
Filename: NASDE 1.jpg
[CLL, lymphoplasmacytoid variant]
74yrs male with clinical diagnosis CLL.  
HISTORY: 2000 WBC 115 (LYMPH 95%); HB 109g/l; RBC 3.7; PLT 110. Hepatosplenomegaly. Leukeran therapy. 2007 progression of CLL.  
BM: B CLL/SLL with Ig lambda expression/restriction and IgM>IgD expression, 90% of the BM space.  
IH: CD20/CD23 (+/++) 40%, CD5(+/++) 80%, CD43/CyclinD1(-), Ki67+ <5% (++++), CD3(-)(except T), Mum1(+/++) 10%, Ig lambda (+/++)>>>Ig kappa, IgM 80%>> IgD(+)30%. Single CD138+ plasmacytes.  
QUESTION: Plasmoid differentiation and IgM+>>IgD inerpretation.  
 
PLEASE FIND SIMILAR CASE, NAMED "CLL and LIKE: Part 2".  
Thank you.
Sender: ugnius
2007-09-25 10:54
INCTR - EBMWG Hematopathology Online

Last modified: 2007-09-25 10:54:07