26yrs old Lady with bone pains.  
BM: Incidentally interstitial infiltration of small/medium "blasts" are detected: 30%.  
IH: CD34(+++)~ 30% of population: TdT (+++)100%, MPO(+) 100% ???, Bcl2/CD117/CD68/WT1/CD4/CD1a, CD79a (+) ~ 70% (ATYPICAL LARGE and smaller cells), Pax-5 (+/++)(more cells with more pleomorphic nuclei than CD20+ mature lymphocytes).  
TOUCH PREP from BM: atypical lymphoblasts with "floral" lobated nuclei.  
ASPIRATE: Dry tap.  
FLOW: CD10+ CD79a+ MPO- (!!!) population 1%.  
MOLECS: See above in discussion.  
 
RPOPOSAL: Acute B lymhoblastic leukaemia,30%. Immunophenotype: CD34+ TdT+ CD117- Bcl2-CD4- CD79a+ Pax5+. MPO???.  
Question: the visualisation and blastic imunophenotype (M/L) asession in threpines in cases of minimal involvement. Especially MPO. DOUBLE STAINING MPO/Pax-5 and CD10 IN PROGRESS.