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PTCL like CHL CD30/CD15+ (458471) » HE vague nodularity.jpg
Filename: HE vague nodularity.jpg
[PTCL like CHL CD30/CD15+]

THE CASE COMPLETED/UPLOADED:

 

36 yrs old Lady with lateral neck lymph node biopsy (with intraoperative consult).

 

HISTO: A lot of clustered in nodules mononuclear giant cells with cHL IH: LCA(-)(?); OCT2/BOB1(-); CD20(-); CD30/CD15+. Background- slightly pleomorphic T cells with focal CD23 FDC nodular networks and HEV's. IH: fully retained T (CD3/CD2/CD/CD7+; CD10(-); Bcl6+ (focal). EBV LMP1/EBER(-).

 

STRANGE THINGS: Ki67 index much more distributed, than GIANT CELLS. Bcl2 signal FAINT and WEAK in T population. CYTOLOGICALLY T population abnormal and larger than usual. LCA doubtfull, CD3 golgi like (positive) in giant cells (?). "Nishing" in CD7 and CD3(?).

 

MOLECS: Clear B clone !!!

 

MY DOUBT: T NHL (AILT like) with cHL like cells.

 

Thank you.

Sender: ugnius
2013-01-25 09:52
INCTR - EBMWG Hematopathology Online

Last modified: 2013-01-25 09:52:45