We present a new case of the tumor of the left tonsil in a-69-year old female. Two particles of the tonsil were recieved for the histopathological analysis.
Within the lymphoid tissue, areas with both nodular and diffuse proliferation of small lymphocytes (with centrocytoid appearance). Lymphocytes had a prominent nucleoli and moderately rough chromatin whereas the cytoplasm was scanty.
Immunohistochemistry: CD20(+), Bcl2(+), Bcl-6(-), Cyclin D1(-), CD23(-), CD3(-), IgG(+), IgD(-). The remnants of the germ centers showed Bcl-6 positivity with expansion of the marginal zone of the lymphatic follicles.
Clinical diagnosis: Tumor of the tonsil
Histopathological diagnosis: CLL or lymphoma?
Please, give your opinion.