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DD: marginal zone lymphoma transformig to DLBCL versus AILT (5989) » Bcl2 a.jpg
Filename: Bcl2 a.jpg
[DD: marginal zone lymphoma transformig to DLBCL versus AILT]
THE SHORT DESCRIPTION OF THE CASE:  
71yrs old female 2007 04 26 underwent 2,5cm lymph node biopsy with clin diagnosis "lymphoma".  
HISTORY: In the beginning of 2007: LN biopsy: "B marginal zone lymphoma combined with HL like peripheral T cell lymphoma".  
Threpine biopsy results: "reactive changes".  
2007 06 06 2 core biopsies of lymph node was repeated: "T proliferation, most probably peripheral T cell lymphoma or AILT". Full LN biopsy was not done.  
PCR: T and B monoclonal from PRIMARY LN biopsy.  
2008 NEWS: Due to multiple lymph node enlargement the LN biopsy was performed.  
HISTO: Please find the photos.  
IH: HL like. Giant cells" CD30+; CD15-; LCA-; EBV-; Ig kappa+; CD20-/+; CD79a+. Background: CD3+; CD4+>>CD8+. CD23/CD21+ FDC network in nodules. CD10+ population in nodules.  
 
FINAL DIAGNOSIS: Primary event B marginal zone lymphoma with transformation to AILT.  
Thank you for comments in this extraordinary case.
Sender: ugnius
2008-07-14 14:29
INCTR - EBMWG Hematopathology Online

Last modified: 2008-07-14 14:29:14