Woman 82 yrs old. Biopsy from lateral nasal skin.  
CLINICALLY: "MTS" in lungs.  
HISTO: Pleomorphic dermal infiltrate with prominent angiocentricity, focal necrosis insuficcient for DLBCL diagnosis.  
IH: In IH slides CRUSHED BIOPTATE ONLY REMAINS, so quality is suboptimal. INFILTRATE: LCA 100%(+++)(membr.), CD20(+/++) 80% (citopl.), CD3(-)(except T ), CD5(-)(except T, which are CD3+ >> CD5+), CD56(-), Bcl2(++) 80% (citopl.), CyclinD1(-), Bcl6(+)<5% (nuclear), CD10(-), Mum1(+/++) 20% (nuclear), CD23(-), Ki67 prolif. activity 80% (brand. r-ja), CD34/TdT/EBV LPM1(-).  
 
PROPOSED DIAGNOSIS: B lymphoproliferation, most probably LyG (II°)vs DLBCL (LyG III°).  
Thank you for beeing 2gether.