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Reactive changes possibly due to impaired hepatic function or hemolysis, granuloma like areas. (7956) » bone marrow.pdf
Filename: bone marrow.pdf
  case: Reactive changes possibly due to impaired hepatic function or hemolysis, granuloma like areas.
Dear colleagues,  
This case present a 58-years-old male with splenomegaly, high fiver, icterus, very high rate of total bilirubin ( 300 mmol/l), pancytopenia, high IgG, law albumin, no hepatomegaly, no hepatitis markers or other serologic tests in this moment.  
We received clot section of bone marrow with reduced myeloid cells, proliferation of erithroid cells, proliferation of T ly ( CD3, CD7, CD4, and CD8- medium sized T-ly), few large B- ly ( CD20+, CD30-, CD15-, Bcl6-, CD10- , EBV-, kappa-, lambda-), few reactive lymphatic follicles, and "granuloma " like changes.  
Dg question: TCRBCL??T-cell lymphoma??? Reactive changes???  
Please, give us your opinion in this interesting case.  
Thank you!  
 
Sender: nurija
2009-07-20 14:26
INCTR - EBMWG Hematopathology Online
bone marrow  
Dear colleagues,  
First I must to apologize cause I put haematopathology case in this group. This case present a 58-years-old  
male with splenomegaly, high fiver, icterus, very high rate of total bilirubin ( 300 mmol/l), pancytopenia, high  
IgG, law albumin, no hepatomegaly, no hepatitis markers or other serologic tests in this moment.  
We received clot section of bone marrow with reduced myeloid cells, proliferation of erithroid cells,  
proliferation of T ly ( CD3, CD7, CD4, and CD8- medium sized T-ly), few large B- ly ( CD20+, CD30-,  
CD15-, Bcl6-, CD10- , EBV-, kappa-, lambda-), few reactive lymphatic follicles, and "granuloma " like  
changes.  
Dg question: T-cell lymphoma??? Reactive changes???  
Please, give us your opinion in this interesting case.  
Thank you!
bone marrow  
Dear colleagues,  
First I must to apologize cause I put haematopathology case in this group. This case present a 58-years-old  
male with splenomegaly, high fiver, icterus, very high rate of total bilirubin ( 300 mmol/l), pancytopenia, high  
IgG, law albumin, no hepatomegaly, no hepatitis markers or other serologic tests in this moment.  
We received clot section of bone marrow with reduced myeloid cells, proliferation of erithroid cells,  
proliferation of T ly ( CD3, CD7, CD4, and CD8- medium sized T-ly), few large B- ly ( CD20+, CD30-,  
CD15-, Bcl6-, CD10- , EBV-, kappa-, lambda-), few reactive lymphatic follicles, and "granuloma " like  
changes.  
Dg question: T-cell lymphoma??? Reactive changes???  
Please, give us your opinion in this interesting case.  
Thank you!