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CLL, lymphoplasmacytoid variant (3783) »
IgD.jpg
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Filename:
IgD.jpg
[
CLL, lymphoplasmacytoid variant
]
74yrs male with clinical diagnosis CLL.
HISTORY: 2000 WBC 115 (LYMPH 95%); HB 109g/l; RBC 3.7; PLT 110. Hepatosplenomegaly. Leukeran therapy. 2007 progression of CLL.
BM: B CLL/SLL with Ig lambda expression/restriction and IgM>IgD expression, 90% of the BM space.
IH: CD20/CD23 (+/++) 40%, CD5(+/++) 80%, CD43/CyclinD1(-), Ki67+ <5% (++++), CD3(-)(except T), Mum1(+/++) 10%, Ig lambda (+/++)>>>Ig kappa, IgM 80%>> IgD(+)30%. Single CD138+ plasmacytes.
QUESTION: Plasmoid differentiation and IgM+>>IgD inerpretation.
PLEASE FIND SIMILAR CASE, NAMED "CLL and LIKE: Part 2".
Thank you.
Sender:
ugnius
2007-09-25 11:02
INCTR - EBMWG Hematopathology Online
original image:
IgD.jpg
(84.3 KB)
Last modified:
2007-09-25 11:02:53
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