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BM biopsy (1673) » Fibrosis IV.jpg
Filename: Fibrosis IV.jpg
[BM biopsy]
BM biopsy (clot) to 74yrs male was performed. CLIN. INFO: Philadelphia chromosome (-), splenomegaly, pancytopenia, Hb 96 g/, Platelets 21, leukocytes 8,0 without left shift, the lack of normoblasts. BM aspirate with expanded granulopoesis with left shift, megakaryocytosis, single micromegakaryocytes. There are any skin rush.  
CLIN DGN: IDIOPATIC MYELOFIBROSIS?  
HISTO: on photos bellow.  
IH: spindle, "epithelioid" clear cells with ovoid nuclei are CD117+++, CD68+ (I've not mast cell tryptase).  
PROPOSED DIAGNOSIS: Chronic myloproliferative disease (cellular myelofibrosis?) with systemic mastocytosis vs systemic mastocytosis only.  
Sender: ugnius
2006-03-22 15:12
INCTR - EBMWG Hematopathology Online

Last modified: 2006-03-22 15:12:36