67 yrs old lady with long story of B CLL/SLL (in 2013 threpine with 30% invoilvement: NOT INCLUDED here).
Lymph node biopsy was performed (1.2cm; location ND).
HISTO: Diffuse and vaguelly nodular architecture, reminescent of "accelerated" B CLL. Interstitial multiple "immunoblastoid" and giant cells with EBER+ CD30+ Pax5+ faint CD15(-) BOB1/Oct2+ attenuated B programme (CHL like).
Context: CD23+ CD5+ small medium B CLL/SLL population.
PROPOSED DIAGNOSIS: B Aggressive lymphoma/Richter's (B CLL/SLL) transformation in the context of B CLL/SLL (accelerated/progression phase).
QUESTION: a DEFINITE name of this Richter;s: "T cell rich B cell lymphoma EBV+, CHL like"? Or maybe Accelerated B CLL/SLL with EBER+ cells and high Ki67 index?