The case for documentation devoted for our friend LT in hematopath R. Juškevičius (US):  
 
46yrs male with unexplainable axillary lymphadenopathy and fever only. Hematoevaluation in progress.  
 
HISTO: AILT (pattern II): expanded vaguelly nodular T areas with HEV and prominent atypia. residual small follicles displaced to periphery. CD10+Bcl6+PD1+ cells around residual folllicles and HEV. CD21+ FDC proliferates displaced to periphery.  
 
EBER scattered/interstitial LARGE nuclei (probably transformed B cells).  
 
DGN.: AILT (pattern II( in the lymph node.  
Immuinophenotype: Bcl2+ (dim); CD3/CD2/CD5/CD4+; > PD1/CD10/Bcl6+; CD7/CD8/GranzymB(-); ALK1/CD30/EBV LMP1(-); Ki67 up to 65%.  
 
 
 

tzankov 2016-11-24 09:01

I fully agree with the diagnosis of AITL