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trephine biopsy (830580)

trephine biopsy

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lotodo

2017-02-10 07:08
INCTR - EBMWG Hematopathology Online

15yr old male with marked pancytopenia, splenomegally 4cm,no lymphadenopathy,persistent fevers, dry tap on aspirate

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tzankov 2017-02-10 17:44	total replacement of the hematopiesis by a histocyte-rich process with scattered centroblastoid cells. One DD that has to be immediately verified/falsified is mycobacterial "pseudosarcoma" - plase stain the case with PAS and ZN. Storage diseases must be ruled out as well - Giemsa, D-PAS? Of couse the case has to be worked-up with basic immunohistochemisty including CD3, CD20, CD30, CD68, S100
lotodo 2017-02-10 19:20	Thank you for your comment,will order for the stains,was wondering if Hodgkins disease would be a differntial
tzankov 2017-02-13 07:14	Yes, Hodgkin is a DD, therefore - CD30

Last modified: 2017-02-10 07:08:19